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Carnitine acetyltransferase in pea cotyledon mitochondria

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Diaz and colleagues concluded that in conditions where it does not increase glucose oxidation, carnitine supplementation worsens both injury and recovery of contractile function after transient ischemia in perfused rat heart [122]

Think of it as a shuttle bus: it moves the fuel to the furnace, but the furnace (exercise, metabolic demand) still has to be running

Pharmacol Ther (2014) 141:1509

Fecal excretion of total carnitine was less than 1% of the administered dose.10 After attainment of steady state following 4 days of oral administration of levocarnitine tablets (1980 mg every 12 hours) or oral solution (2000 mg every 12 hours) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12 hours) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)